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Substitution of the Native Zn(II) with Cd(II), Co(II) and Ni(II) Changes the Downhill Unfolding Mechanism of Ros87 to a Completely Different Scenario

The structural effects of zinc replacement by xenobiotic metal ions have been widely studied in several eukaryotic and prokaryotic zinc-finger-containing proteins. The prokaryotic zinc finger, that presents a bigger βββαα domain with a larger hydrophobic core with respect to its eukaryotic counterpa...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Grazioso, Rinaldo, García-Viñuales, Sara, Russo, Luigi, D’Abrosca, Gianluca, Esposito, Sabrina, Zaccaro, Laura, Iacovino, Rosa, Milardi, Danilo, Fattorusso, Roberto, Malgieri, Gaetano, Isernia, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663847/
https://ncbi.nlm.nih.gov/pubmed/33167398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218285
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