Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Neuroblastoma (NB), derived from the neural crest (NC), is the most common pediatric extracranial solid tumor. Here, we establish a platform that allows the study of human NBs in mouse-human NC chimeras. Chimeric mice were produced by injecting human NC cells carrying NB relevant oncogenes in utero...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Cohen, Malkiel A., Zhang, Shupei, Sengupta, Satyaki, Ma, Haiting, Bell, George W., Horton, Brendan, Sharma, Bandana, George, Rani E., Spranger, Stefani, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663823/
https://ncbi.nlm.nih.gov/pubmed/32142683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.02.001
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