Multidisciplinary Treatment, Including Locoregional Chemotherapy, for Merkel-Polyomavirus-Positive Merkel Cell Carcinomas: Perspectives for Patients Exhibiting Oncogenic Alternative Δ exon 6–7 TrkAIII Splicing of Neurotrophin Receptor Tropomyosin-Related Kinase A

Merkel cell carcinomas (MCCs) are rare, aggressive, cutaneous neuroendocrine tumours, approximately 80% of which are caused by the genomic integration of Merkel cell polyomavirus (MCPyV). MCPyV-positive MCCs carry poor prognosis in approximately 70% of cases, highlighting the need for greater unders...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Guadagni, Stefano, Farina, Antonietta Rosella, Cappabianca, Lucia Annamaria, Sebastiano, Michela, Maccarone, Rita, Zelli, Veronica, Clementi, Marco, Chiominto, Alessandro, Bruera, Gemma, Ricevuto, Enrico, Fiorentini, Giammaria, Sarti, Donatella, Mackay, Andrew Reay
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662965/
https://ncbi.nlm.nih.gov/pubmed/33153070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218222
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