Putative Origins of Cell-Free DNA in Humans: A Review of Active and Passive Nucleic Acid Release Mechanisms

Through various pathways of cell death, degradation, and regulated extrusion, partial or complete genomes of various origins (e.g., host cells, fetal cells, and infiltrating viruses and microbes) are continuously shed into human body fluids in the form of segmented cell-free DNA (cfDNA) molecules. W...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Grabuschnig, Stefan, Bronkhorst, Abel Jacobus, Holdenrieder, Stefan, Rosales Rodriguez, Ingund, Schliep, Klaus Peter, Schwendenwein, Daniel, Ungerer, Vida, Sensen, Christoph Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662960/
https://ncbi.nlm.nih.gov/pubmed/33137955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218062
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