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Extracellular vesicles from amyloid-β exposed cell cultures induce severe dysfunction in cortical neurons

Alzheimer’s disease (AD) is characterized by a substantial loss of neurons and synapses throughout the brain. The exact mechanism behind the neurodegeneration is still unclear, but recent data suggests that spreading of amyloid-β (Aβ) pathology via extracellular vesicles (EVs) may contribute to dise...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Beretta, Chiara, Nikitidou, Elisabeth, Streubel-Gallasch, Linn, Ingelsson, Martin, Sehlin, Dag, Erlandsson, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661699/
https://ncbi.nlm.nih.gov/pubmed/33184307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72355-2
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