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LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α

Epigenetic alteration is one of the hallmarks of colorectal cancer (CRC). Many driver genes are regulated by DNA methylation in CRC. However, the role of DNA methylation regulating lncRNAs remain elusive. Here, we identify that SNHG11 (small nucleolar RNA host gene 11) is upregulated by promotor hyp...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Xu, Linguo, Huan, Lin, Guo, Tianan, Wu, Yangjun, Liu, Yanfang, Wang, Qifeng, Huang, Shenglin, Xu, Ye, Liang, Linhui, He, Xianghuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661343/
https://ncbi.nlm.nih.gov/pubmed/33060856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01512-8
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