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Leptin down-regulates KCC2 activity and controls chloride homeostasis in the neonatal rat hippocampus

The canonical physiological role of leptin is to regulate hunger and satiety acting on specific hypothalamic nuclei. Beyond this key metabolic function; leptin also regulates many aspects of development and functioning of neuronal hippocampal networks throughout life. Here we show that leptin contro...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Brain
Hauptverfasser: Dumon, Camille, Belaidouni, Yasmine, Diabira, Diabe, Appleyard, Suzanne M., Wayman, Gary A., Gaiarsa, Jean-Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661183/
https://ncbi.nlm.nih.gov/pubmed/33183317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00689-z
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