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Leptin down-regulates KCC2 activity and controls chloride homeostasis in the neonatal rat hippocampus

The canonical physiological role of leptin is to regulate hunger and satiety acting on specific hypothalamic nuclei. Beyond this key metabolic function; leptin also regulates many aspects of development and functioning of neuronal hippocampal networks throughout life. Here we show that leptin contro...

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Publicat a:Mol Brain
Autors principals: Dumon, Camille, Belaidouni, Yasmine, Diabira, Diabe, Appleyard, Suzanne M., Wayman, Gary A., Gaiarsa, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661183/
https://ncbi.nlm.nih.gov/pubmed/33183317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00689-z
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