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Clinical Significance of Down-Regulated CD70 and CD27 Expression in Poor Prognosis of Esophageal Squamous Cell Carcinoma

INTRODUCTION: CD27 is a co-stimulatory immune checkpoint molecule in the tumor necrosis factor receptor superfamily. CD27 regulates the generation and maintenance of T cell immunity by binding to CD70 and regulating B-cell activation and immunoglobulin synthesis. MATERIALS AND METHODS: CD27 and CD70...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Shan, Ting-ting, Zhao, Xuan, Zhang, Zhen, Wang, Jing-pu, Zhang, Yi, Yang, Yang, Zhao, Song
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660989/
https://ncbi.nlm.nih.gov/pubmed/33204151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S241377
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