Gut Microbiota‐Dependent Trimethylamine N‐oxide and Cardiovascular Outcomes in Patients With Prior Myocardial Infarction: A Nested Case Control Study From the PEGASUS‐TIMI 54 Trial

BACKGROUND: Trimethylamine N‐oxide (TMAO) may have prothrombotic properties. We examined the association of TMAO quartiles with major adverse cardiovascular events (MACE) and the effect of TMAO on the efficacy of ticagrelor. METHODS AND RESULTS: PEGASUS‐TIMI 54 (Prevention of Cardiovascular Events i...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Gencer, Baris, Li, Xinmin S., Gurmu, Yared, Bonaca, Marc P., Morrow, David A., Cohen, Marc, Bhatt, Deepak L., Steg, P. Gabriel, Storey, Robert F., Johanson, Per, Wang, Zeneng, Hazen, Stanley L., Sabatine, Marc S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660879/
https://ncbi.nlm.nih.gov/pubmed/32366163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015331
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