Evolocumab, a PCSK9‐Monoclonal Antibody, Rapidly Reverses Coronary Artery Endothelial Dysfunction in People Living With HIV and People With Dyslipidemia

BACKGROUND: PCSK9 (proprotein convertase subtilisin/kexin type 9) is well recognized for its important role in cholesterol metabolism. Elevated levels are associated with increased cardiovascular risk and inhibition with PCSK9 antibodies (PCSK9i) lowers cardiovascular events in patients with coronar...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Leucker, Thorsten M., Gerstenblith, Gary, Schär, Michael, Brown, Todd T., Jones, Steven R., Afework, Yohannes, Weiss, Robert G., Hays, Allison G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660736/
https://ncbi.nlm.nih.gov/pubmed/32674634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.016263
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