Topoisomerase activity is linked to altered nucleosome positioning and transcriptional regulation in the fission yeast fbp1 gene

Chromatin structure, including nucleosome positioning, has a fundamental role in transcriptional regulation through influencing protein-DNA interactions. DNA topology is known to influence chromatin structure, and in doing so, can also alter transcription. However, detailed mechanism(s) linking tran...

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Udgivet i:PLoS One
Main Authors: Asada, Ryuta, Senmatsu, Satoshi, Montpetit, Ben, Hirota, Kouji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660550/
https://ncbi.nlm.nih.gov/pubmed/33180846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242348
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