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Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels

Progression of epithelial cancers predominantly proceeds by collective invasion of cell groups with coordinated cell–cell junctions and multicellular cytoskeletal activity. Collectively invading breast cancer cells express the gap junction protein connexin-43 (Cx43), yet whether Cx43 regulates colle...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Khalil, Antoine A., Ilina, Olga, Vasaturo, Angela, Venhuizen, Jan-Hendrik, Vullings, Manon, Venhuizen, Victor, Bilos, Ab, Figdor, Carl G., Span, Paul N., Friedl, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659730/
https://ncbi.nlm.nih.gov/pubmed/32777015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201911120
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