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Nesprin-2G tension fine-tunes Wnt/β-catenin signaling

How LINC complexes mediate nuclear mechanotransduction remains unclear. In this issue, Déjardin, Carollo, et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201908036) show that the LINC complex protein nesprin-2G is a mechanosensor of epithelial–mesenchymal transitions (EMTs), recruiting α-cat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Gottardi, Cara J., Luxton, G.W. Gant
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659724/
https://ncbi.nlm.nih.gov/pubmed/32966550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202009042
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