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Senescence Inflames the Pancreatic Tumor Microenvironment
Pancreatic adenocarcinomas (PDACs) are scarcely vascularized and thus virtually insensitive to chemotherapy and immunotherapy. In a recent issue of Cell, Lowe and collaborators(1) have demonstrated that senescence induction by MEK plus CDK4/CDK6 inhibitors favors PDAC revascularization coupled to in...
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| Publicat a: | Cell Rep Med |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659541/ https://ncbi.nlm.nih.gov/pubmed/33205059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100020 |
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