A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea

Stress is a known trigger for flares of inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS); however, this process is not well understood. Here, we find that restraint stress in mice leads to signs of diarrhea, fecal dysbiosis, and a barrier defect via the opening of goblet-cell asso...

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Publicado en:Cell Rep Med
Main Authors: Rengarajan, Sunaina, Knoop, Kathryn A., Rengarajan, Arvind, Chai, Jiani N., Grajales-Reyes, Jose G., Samineni, Vijay K., Russler-Germain, Emilie V., Ranganathan, Prabha, Fasano, Alessio, Sayuk, Gregory S., Gereau, Robert W., Kau, Andrew L., Knights, Dan, Kashyap, Purna C., Ciorba, Matthew A., Newberry, Rodney D., Hsieh, Chyi-Song
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659537/
https://ncbi.nlm.nih.gov/pubmed/33196055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100124
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