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Dissecting the Role of GABA Neurons in the VTA versus SNr in Opioid Reward

Opioid reward has traditionally been thought to be mediated by GABA-induced disinhibition of dopamine (DA) neurons in the VTA. However, direct behavioral evidence supporting this hypothesis is still lacking. In this study, we found that the μ opioid receptor (MOR) gene, Oprm1, is highly expressed in...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Galaj, Ewa, Han, Xiao, Shen, Hui, Jordan, Chloe J., He, Yi, Humburg, Bree, Bi, Guo-Hua, Xi, Zheng-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659457/
https://ncbi.nlm.nih.gov/pubmed/33046548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0988-20.2020
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