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Bioequivalence of perampanel fine granules and tablets in healthy Japanese subjects

Objective: Perampanel is an approved anti-seizure drug. A new formulation of perampanel fine granules (FG; 1% perampanel) has been developed for patients who are unable to take tablets. Bioequivalence between the 4-mg FG and tablet perampanel formulations, as well as their safety and tolerability, w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Pharmacol Ther
Hauptverfasser: Shiba, Sari, Sekino, Hisakuni, Ishiba, Kaeko, Yasuda, Sanae, Inoue, Syuhei, Kotaka, Ken, Reyderman, Larisa, Uchida, Naoki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dustri-Verlag Dr. Karl Feistle 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659282/
https://ncbi.nlm.nih.gov/pubmed/32870153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5414/CP203781
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