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Specific populations of urinary extracellular vesicles and proteins differentiate type 1 primary hyperoxaluria patients without and with nephrocalcinosis or kidney stones

BACKGROUND: Primary hyperoxaluria type 1 (PH1) is associated with nephrocalcinosis (NC) and calcium oxalate (CaOx) kidney stones (KS). Populations of urinary extracellular vesicles (EVs) can reflect kidney pathology. The aim of this study was to determine whether urinary EVs carrying specific biomar...

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Publicado en:Orphanet J Rare Dis
Autores principales: Jayachandran, Muthuvel, Yuzhakov, Stanislav V., Kumar, Sanjay, Larson, Nicholas B., Enders, Felicity T., Milliner, Dawn S., Rule, Andrew D., Lieske, John C.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659070/
https://ncbi.nlm.nih.gov/pubmed/33176829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-020-01607-1
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