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Ensemble description of the intrinsically disordered N-terminal domain of the Nipah virus P/V protein from combined NMR and SAXS

Using SAXS and NMR spectroscopy, we herein provide a high-resolution description of the intrinsically disordered N-terminal domain (PNT, aa 1–406) shared by the Nipah virus (NiV) phosphoprotein (P) and V protein, two key players in viral genome replication and in evasion of the host innate immune re...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Schiavina, Marco, Salladini, Edoardo, Murrali, Maria Grazia, Tria, Giancarlo, Felli, Isabella C., Pierattelli, Roberta, Longhi, Sonia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658984/
https://ncbi.nlm.nih.gov/pubmed/33177626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76522-3
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