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Composition and Function of Telomerase—A Polymerase Associated with the Origin of Eukaryotes

The canonical DNA polymerases involved in the replication of the genome are unable to fully replicate the physical ends of linear chromosomes, called telomeres. Chromosomal termini thus become shortened in each cell cycle. The maintenance of telomeres requires telomerase—a specific RNA-dependent DNA...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomolecules
Prif Awduron: Schrumpfová, Petra Procházková, Fajkus, Jiří
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658794/
https://ncbi.nlm.nih.gov/pubmed/33050064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10101425
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