Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control

The death of cardiomyocytes either through apoptosis or necroptosis is the pathological feature of cardiac ischemia-reperfusion (I/R) injury. Phosphoglycerate mutase 5 (PGAM5), a mitochondrially-localized serine/threonine-protein phosphatase, functions as a novel inducer of necroptosis. However, int...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Zhu, Hang, Tan, Ying, Du, Wenjun, Li, Yang, Toan, Sam, Mui, David, Tian, Feng, Zhou, Hao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658715/
https://ncbi.nlm.nih.gov/pubmed/33166869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101777
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