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Intratumor Heterogeneity of MYO18A and FBXW7 Variants Impact the Clinical Outcome of Stage III Colorectal Cancer

Many studies failed to demonstrate benefit from the addition of targeted agents to current standard adjuvant FOLFOX chemotherapy in stage III colorectal cancer (CRC) patients. Intratumor heterogeneity may foster the resistant subclones and leads to cancer recurrence. Here, we built a cancer evolutio...

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Publicat a:Front Oncol
Autors principals: Lin, Peng-Chan, Yeh, Yu-Min, Lin, Bo-Wen, Lin, Shao-Chieh, Chan, Ren-Hao, Chen, Po-Chuan, Shen, Meng-Ru
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658598/
https://ncbi.nlm.nih.gov/pubmed/33194745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.588557
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