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Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review)

Viruses are obligate intracellular parasites and have evolved to enter the host cell. To gain access they come into contact with the host cell through an initial adhesion, and some viruses from different genus may use heparan sulfate proteoglycans for it. The successful inhibition of this early even...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Egorova, Anna, Bogner, Elke, Novoselova, Elena, Zorn, Kimberley M., Ekins, Sean, Makarov, Vadim
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Masson SAS. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658596/
https://ncbi.nlm.nih.gov/pubmed/33218683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.113014
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