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In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH

Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lack of robust methods to track AAV capsids and genom...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Wang, Sean K., Lapan, Sylvain W., Hong, Christin M., Krause, Tyler B., Cepko, Constance L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658570/
https://ncbi.nlm.nih.gov/pubmed/33209963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.10.003
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