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Interplay between reactive oxygen species and autophagy in the course of age-related macular degeneration

Pathological biomolecules such as lipofuscin, methylglyoxal-modified proteins (the major precursors of advanced glycationend products), misfolding protein deposits and dysfunctional mitochondria are source of oxidative stress and act as strong autophagic stimulators in age-related macular degenerati...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Nita, Malgorzata, Grzybowski, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658465/
https://ncbi.nlm.nih.gov/pubmed/33192217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-2915
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