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Derivation and Differentiation of Adipose-Tissue Regulatory T Cells: A Stepwise, Multi-Site Process

CD4(+) Foxp3(+) regulatory T cells (Tregs) not only enforce peripheral tolerance and restrain self-reactive immune responses, but also maintain organismal homeostasis and safeguard the function of parenchymal tissues. A paradigmatic tissue–Treg population resides in the visceral adipose tissue (VAT)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sivasami, Pulavendran, Li, Chaoran
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658365/
https://ncbi.nlm.nih.gov/pubmed/33193452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.599277
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