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The cryo-EM structure of a γ-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems

The nucleation of microtubules from αβ-tubulin subunits is mediated by γ-tubulin complexes, which vary in composition across organisms. Aiming to understand how de novo microtubule formation is achieved and regulated by a minimal microtubule nucleation system, we here determined the cryo-electron mi...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zupa, Erik, Zheng, Anjun, Neuner, Annett, Würtz, Martin, Liu, Peng, Böhler, Anna, Schiebel, Elmar, Pfeffer, Stefan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658347/
https://ncbi.nlm.nih.gov/pubmed/33177498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19456-8
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