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Distinct regional ontogeny and activation of tumor associated macrophages in human glioblastoma

Tumor-associated macrophages (TAMs) constitute up to 50% of tumor bulk in glioblastoma (GBM) and play an important role in tumor maintenance and progression. The recently discovered differences between invading tumour periphery and hypoxic tumor core implies that macrophage biology is also distinct...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Landry, Alexander P., Balas, Michael, Alli, Saira, Spears, Julian, Zador, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658345/
https://ncbi.nlm.nih.gov/pubmed/33177572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76657-3
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