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IL-22 ameliorates LPS-induced acute liver injury by autophagy activation through ATF4-ATG7 signaling

Uncontrollable inflammatory response acts as a driver of sepsis-associated liver injury (SALI). IL-22 plays an important role in regulating inflammatory responses, but its role in SALI remains unknown. The aim of the study was to assess the association of serum IL-22 with SALI in pediatric patients...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shao, Lujing, Xiong, Xi, Zhang, Yucai, Miao, Huijie, Ren, Yuqian, Tang, Xiaomeng, Song, Jia, Wang, Chunxia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658242/
https://ncbi.nlm.nih.gov/pubmed/33177520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03176-4
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