Integration of metabolomics and transcriptomics reveals novel biomarkers in the blood for tuberculosis diagnosis in children

Pediatric tuberculosis (TB) remains a major global health problem. Improved pediatric diagnostics using readily available biosources are urgently needed. We used liquid chromatography-mass spectrometry to analyze plasma metabolite profiles of Indian children with active TB (n = 16) and age- and sex-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Dutta, Noton K., Tornheim, Jeffrey A., Fukutani, Kiyoshi F., Paradkar, Mandar, Tiburcio, Rafael T., Kinikar, Aarti, Valvi, Chhaya, Kulkarni, Vandana, Pradhan, Neeta, Shivakumar, Shri Vijay Bala Yogendra, Kagal, Anju, Gupte, Akshay, Gupte, Nikhil, Mave, Vidya, Gupta, Amita, Andrade, Bruno B., Karakousis, Petros C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658223/
https://ncbi.nlm.nih.gov/pubmed/33177551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75513-8
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