SARS-CoV-2 receptor is co-expressed with elements of the kinin–kallikrein, renin–angiotensin and coagulation systems in alveolar cells

SARS-CoV-2, the pathogenic agent of COVID-19, employs angiotensin converting enzyme-2 (ACE2) as its cell entry receptor. Clinical data reveal that in severe COVID-19, SARS-CoV-2 infects the lung, leading to a frequently lethal triad of respiratory insufficiency, acute cardiovascular failure, and coa...

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Hlavní autoři: Sidarta-Oliveira, Davi, Jara, Carlos Poblete, Ferruzzi, Adriano J., Skaf, Munir S., Velander, William H., Araujo, Eliana P., Velloso, Licio A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658217/
https://ncbi.nlm.nih.gov/pubmed/33177594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76488-2
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