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Recurring urothelial carcinomas show genomic rearrangements incompatible with a direct relationship

We used the fact that patients with non-muscle invasive bladder tumors show local recurrences and multiple tumors to study re-initiation of tumor growth from the same urothelium. By extensive genomic analyses we show that tumors from the same patient are clonal. We show that gross genomic chromosoma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marzouka, Nour-Al-Dain, Lindgren, David, Eriksson, Pontus, Sjödahl, Gottfrid, Bernardo, Carina, Liedberg, Fredrik, Axelson, Håkan, Höglund, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658206/
https://ncbi.nlm.nih.gov/pubmed/33177554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75854-4
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