Adjunctive Cenobamate for Focal-Onset Seizures in Adults: A Systematic Review and Meta-Analysis

BACKGROUND: Cenobamate is a novel tetrazole-derived carbamate compound with a dual mechanism of action. This drug can enhance the inactivated state of voltage-gated sodium channels, preferentially inhibiting the persistent component of the sodium channel current, and acts as a positive allosteric mo...

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Bibliografiske detaljer
Udgivet i:CNS Drugs
Main Authors: Lattanzi, Simona, Trinka, Eugen, Zaccara, Gaetano, Striano, Pasquale, Del Giovane, Cinzia, Silvestrini, Mauro, Brigo, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Systematic Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658084/
https://ncbi.nlm.nih.gov/pubmed/32851590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-020-00759-9
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