The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: Escherichia coli Deficient in RpoS as a Colonization Probe

Pluripotent stem-cell-derived human intestinal organoids (HIOs) are three-dimensional, multicellular structures that model a naive intestinal epithelium in an in vitro system. Several published reports have investigated the use of HIOs to study host-microbe interactions. We recently demonstrated tha...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Barron, Madeline R., Cieza, Roberto J., Hill, David R., Huang, Sha, Yadagiri, Veda K., Spence, Jason R., Young, Vincent B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657587/
https://ncbi.nlm.nih.gov/pubmed/33177212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00777-20
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