Expression of signal-transducing adaptor protein-1 attenuates experimental autoimmune hepatitis via down-regulating activation and homeostasis of invariant natural killer T cells

OBJECTIVE: Signal-transducing adaptor protein (STAP) family members function as adaptor molecules and are involved in several events during immune responses. Notably however, the biological functions of STAP-1 in other cells are not known. We aimed to investigate the functions of STAP-1 in invariant...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kashiwakura, Jun-ichi, Saitoh, Kodai, Ihara, Takeru, Sasaki, Yuto, Kagohashi, Kota, Enohara, Shiyo, Morioka, Yuka, Watarai, Hiroshi, Muromoto, Ryuta, Kitai, Yuichi, Iwabuchi, Kazuya, Oritani, Kenji, Matsuda, Tadashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657518/
https://ncbi.nlm.nih.gov/pubmed/33175848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241440
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