High expression of KIBRA in low atypical protein kinase C‐expressing gastric cancer correlates with lymphatic invasion and poor prognosis

Overexpression of atypical protein kinase Cλ/ι (aPKCλ/ι), a regulator of cell polarity, is frequently associated with the poor prognoses of several cancers, including gastric cancer. Recent studies revealed a molecular link between aPKC and KIBRA, an upstream regulator of tumor suppressor Hippo path...

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Publicat a:Cancer Sci
Autors principals: Yoshihama, Yohei, Izumisawa, Yusuke, Akimoto, Kazunori, Satoh, Yoshinori, Mizushima, Taichi, Satoh, Kei, Chida, Kazuhiro, Takagawa, Ryo, Akiyama, Hirotoshi, Ichikawa, Yasushi, Kunisaki, Chikara, Inayama, Yoshiaki, Endo, Itaru, Nagashima, Yoji, Ohno, Shigeo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2012
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657249/
https://ncbi.nlm.nih.gov/pubmed/23163744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12066
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