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Novel adaptor protein Shf interacts with ALK receptor and negatively regulates its downstream signals in neuroblastoma

Our neuroblastoma cDNA project previously identified Src homology 2 domain containing F (Shf) as one of the genes expressed at high levels in favorable neuroblastoma. Shf is an adaptor protein containing four putative tyrosine phosphorylation sites and an SH2 domain. In this study, we found that Shf...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Takagi, Daisuke, Tatsumi, Yasutoshi, Yokochi, Tomoki, Takatori, Atsushi, Ohira, Miki, Kamijo, Takehiko, Kondo, Satoshi, Fujii, Yoshitaka, Nakagawara, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657181/
https://ncbi.nlm.nih.gov/pubmed/23360421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12115
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