Novel adaptor protein Shf interacts with ALK receptor and negatively regulates its downstream signals in neuroblastoma

Our neuroblastoma cDNA project previously identified Src homology 2 domain containing F (Shf) as one of the genes expressed at high levels in favorable neuroblastoma. Shf is an adaptor protein containing four putative tyrosine phosphorylation sites and an SH2 domain. In this study, we found that Shf...

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Publicado en:Cancer Sci
Autores principales: Takagi, Daisuke, Tatsumi, Yasutoshi, Yokochi, Tomoki, Takatori, Atsushi, Ohira, Miki, Kamijo, Takehiko, Kondo, Satoshi, Fujii, Yoshitaka, Nakagawara, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2013
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657181/
https://ncbi.nlm.nih.gov/pubmed/23360421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12115
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