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Low molecular weight heparin suppresses receptor for advanced glycation end products‐mediated expression of malignant phenotype in human fibrosarcoma cells

The receptor for advanced glycation end products (RAGE) is a pattern‐recognition receptor and its engagement by ligands such as high mobility group box 1 (HMGB1) is implicated in tumor growth and metastasis. Low molecular weight heparin (LMWH) has an antagonistic effect on the RAGE axis and is also...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Takeuchi, Akihiko, Yamamoto, Yasuhiko, Munesue, Seiichi, Harashima, Ai, Watanabe, Takuo, Yonekura, Hideto, Yamamoto, Hiroshi, Tsuchiya, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657155/
https://ncbi.nlm.nih.gov/pubmed/23421467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12133
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