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Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma

Genetic alterations and deregulation of the miRNA biogenesis pathway components have been reported in human tumors. Tissue‐specific deletion of the Dicer gene, which encodes an essential miRNA processing enzyme, promotes carcinogenesis in animal models. These features indicate that aberrant miRNA bi...

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Vydáno v:Cancer Sci
Hlavní autoři: Kitagawa, Noriyuki, Ojima, Hidenori, Shirakihara, Takuya, Shimizu, Hiroko, Kokubu, Akiko, Urushidate, Tomoko, Totoki, Yasushi, Kosuge, Tomoo, Miyagawa, Shinichi, Shibata, Tatsuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657122/
https://ncbi.nlm.nih.gov/pubmed/23398123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12126
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