Adjunctive sertraline for asymptomatic cryptococcal antigenemia: A randomized clinical trial

Cryptococcal antigen (CrAg) screening in HIV-infected persons with CD4 < 100 cells/µl can reduce meningitis and death, yet preemptive fluconazole therapy fails in ∼25%. Sertraline has in vitro and in vivo activity against Cryptococcus and is synergistic with fluconazole in mice. We evaluated the...

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Detalhes bibliográficos
Publicado no:Med Mycol
Main Authors: Boulware, David R, Nalintya, Elizabeth, Rajasingham, Radha, Kirumira, Paul, Naluyima, Rose, Turya, Fred, Namanda, Sylvia, Rutakingirwa, Morris K, Skipper, Caleb P, Nikweri, Yofesi, Hullsiek, Kathy Huppler, Bangdiwala, Ananta S, Meya, David B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657093/
https://ncbi.nlm.nih.gov/pubmed/32415846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mmy/myaa033
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