Epigenetic silencing of HTLV-1 expression by the HBZ RNA through interference with the basal transcription machinery

By disrupting basal transcription machinery, HBZ RNA inhibits sense transcription of human T-cell leukemia virus type 1. Repression of genomic expression may allow entry into proviral latency and escape from immune response.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Gazon, Hélène, Chauhan, Pradeep Singh, Porquet, Florent, Hoffmann, Gabriela Brunsting, Accolla, Roberto, Willems, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Stimulus Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656924/
https://ncbi.nlm.nih.gov/pubmed/33170933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001675
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