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Understanding the causes of errors in eukaryotic protein-coding gene prediction: a case study of primate proteomes

BACKGROUND: Recent advances in sequencing technologies have led to an explosion in the number of genomes available, but accurate genome annotation remains a major challenge. The prediction of protein-coding genes in eukaryotic genomes is especially problematic, due to their complex exon–intron struc...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Meyer, Corentin, Scalzitti, Nicolas, Jeannin-Girardon, Anne, Collet, Pierre, Poch, Olivier, Thompson, Julie D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656754/
https://ncbi.nlm.nih.gov/pubmed/33172385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03855-1
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