Bone marrow mesenchymal stem cell-derived exosomes promote plasminogen activator inhibitor 1 expression in vascular cells in the local microenvironment during rabbit osteonecrosis of the femoral head

BACKGROUND: Nontraumatic osteonecrosis of the femoral head (NONFH) is a highly disabling orthopedic disease in young individuals. Plasminogen activator inhibitor 1 (PAI-1) has been reported to be positively associated with NONFH. We aimed to investigate the dysregulating PAI-1 in bone marrow mesench...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Principais autores: Li, Lu, Wang, Yikai, Yu, Xiaobing, Bao, Yongming, An, Lijia, Wei, Xiaowei, Yu, Weiting, Liu, Baoyi, Li, Junlei, Yang, Jiahui, Xia, Yan, Liu, Ge, Cao, Fang, Zhang, Xiuzhi, Zhao, Dewei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656701/
https://ncbi.nlm.nih.gov/pubmed/33176873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01991-2
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