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Inverse correlation between Thr‐669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation

We have recently identified tumor necrosis factor (TNF)‐α‐induced phosphorylation of epidermal growth factor receptor (EGFR) at Thr‐669 and Ser‐1046/1047 via ERK and p38 pathways, respectively. In the present study, we investigated the roles of ligand‐induced phosphorylation of serine and threonine...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Sato, Kanae, Shin, Myoung‐Sook, Sakimura, Ayaka, Zhou, Yue, Tanaka, Tomohiro, Kawanishi, Miho, Kawasaki, Yuki, Yokoyama, Satoru, Koizumi, Keiichi, Saiki, Ikuo, Sakurai, Hiroaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656534/
https://ncbi.nlm.nih.gov/pubmed/23822636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12225
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