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Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy

An incomplete understanding of the molecular mechanisms behind impairment of lung pathobiology by COVID-19 complicates its clinical management. In this study, we analyzed the gene expression pattern of cells obtained from biopsies of COVID-19-affected patient and compared to the effects observed in...

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Publicat a:Sci Rep
Autors principals: Islam, Abul Bashar Mir Md. Khademul, Khan, Md. Abdullah-Al-Kamran
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656460/
https://ncbi.nlm.nih.gov/pubmed/33173052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76404-8
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