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Novel domain expansion methods to improve the computational efficiency of the Chemical Master Equation solution for large biological networks

BACKGROUND: Numerical solutions of the chemical master equation (CME) are important for understanding the stochasticity of biochemical systems. However, solving CMEs is a formidable task. This task is complicated due to the nonlinear nature of the reactions and the size of the networks which result...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Kosarwal, Rahul, Kulasiri, Don, Samarasinghe, Sandhya
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656229/
https://ncbi.nlm.nih.gov/pubmed/33176690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03668-2
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