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Thiostrepton and miR-216b synergistically promote osteosarcoma cell cytotoxicity and apoptosis by targeting FoxM1

Osteosarcoma is a common primary bone cancer that there are currently no effective treatment strategies for. Forkhead box M1 (FoxM1) is key in the development of osteosarcoma, and microRNA (miR)-216b serves an antitumor role by targeting FoxM1. Moreover, thiostrepton (TST), a natural thiazole antibi...

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Publicat a:Oncol Lett
Autors principals: Cai, Xiaobing, Xiao, Wenyu, Shen, Juexin, Lian, Hui, Lu, Yi, Liu, Xianmiao, Gu, Jisheng
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656114/
https://ncbi.nlm.nih.gov/pubmed/33193851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12254
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