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全反式维甲酸调控内质网应激诱导FLT3-ITD蛋白自噬降解促进白血病细胞凋亡

OBJECTIVE: Endoplasmic reticulum stress(ERS)was used as the research emphasis to further investigate the mechanisms of apoptosis of FLT3-ITD-mutated leukemia cells and decreased expression of FLT3-ITD mutated protein induced by all-trans retinoic acid(ATRA). METHODS: FLT3-ITD-mutated leukemia cell l...

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Detalhes bibliográficos
Publicado no:Zhonghua Xue Ye Xue Za Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial office of Chinese Journal of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656071/
https://ncbi.nlm.nih.gov/pubmed/33190441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2020.10.008
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