Synthesis of the Hydroxamate Siderophore N(α)-Methylcoprogen B in Scedosporium apiospermum Is Mediated by sidD Ortholog and Is Required for Virulence

Scedosporium species rank second among the filamentous fungi capable to colonize chronically the respiratory tract of patients with cystic fibrosis (CF). Nevertheless, there is little information on the mechanisms underpinning their virulence. Iron acquisition is critical for the growth and pathogen...

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Опубликовано в: :Front Cell Infect Microbiol
Главные авторы: Le Govic, Yohann, Havlíček, Vladimir, Capilla, Javier, Luptáková, Dominika, Dumas, Dayana, Papon, Nicolas, Le Gal, Solène, Bouchara, Jean-Philippe, Vandeputte, Patrick
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Cellular and Infection Microbiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655970/
https://ncbi.nlm.nih.gov/pubmed/33194829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.587909
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