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Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

Clinical efficacy of treatments against non-obstructive azoospermia (NOA), which affects 1% of men, are currently limited by the incomplete understanding of NOA pathogenesis and normal spermatogenic microenvironment. Here, we profile >80,000 human testicular single-cell transcriptomes from 10 hea...

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Bibliografske podrobnosti
izdano v:	Nat Commun
Main Authors:	Zhao, LiangYu, Yao, ChenCheng, Xing, XiaoYu, Jing, Tao, Li, Peng, Zhu, ZiJue, Yang, Chao, Zhai, Jing, Tian, RuHui, Chen, HuiXing, Luo, JiaQiang, Liu, NaChuan, Deng, ZhiWen, Lin, XiaoHan, Li, Na, Fang, Jing, Sun, Jie, Wang, ChenChen, Zhou, Zhi, Li, Zheng
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group UK 2020
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7655944/ https://ncbi.nlm.nih.gov/pubmed/33173058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19414-4
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Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

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